The leaf of Costus pictus D. Don is considered as an antidiabetic in folklore medicine and is known to reduce the blood sugar, similar to insulin. PDF | To explore the micro morphology and physicochemical parameters of the leaves of Costus pictus D. Don (Costaceae). Macroscopy. Painted Spiral Ginger is a perennial herb, native to Mexico. It has long narrow leaves with a characteristic wavy edges. The bases of the sheaths are mottled with.

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This article has been cited by. The data identified transcripts related to pathways of bixin, geranial and geraniol biosynthesis which are known to be peroxixome proliferator activated receptors PPAR agonists and anti-glycation agents.

The presence of oxidative stress further augments the hepatic and renal damage caused due to thyroid hormone insufficiency. Psychological well-being in patients on ‘adequate’ doses of l-thyroxine: Drug Des Devel Ther.

High-performance liquid chromatography chromatogram of a estrone Internal standard for analysis of terpenes b Costus pictus extract. These results clearly demonstrate that C.


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Int J Curr Pharm Res. The bases of the sheaths are mottled with markings that have earned the plant the synonym of Costus hieroglyphica. Differences between the groups were analyzed cosyus one-way analysis of variance with Bonferroni post hoc test. Alanine aminotransferase; C group: All other chemicals used were of analytical grade obtained from SRL India.

The preventive effect of Costus pictus leaf extract in experimental hypothyroidism was evaluated in the present study. For detection and quantification, HPLC system was coupled with a Thermo Fisher TSQ Vantage triple quadrupole mass spectrometer, operated with atmospheric pressure chemical ionization positive.

Diabetes Vs herbal medicines.

Costus pictus ‘Red Stem’ – Gingerwood Nursery

How to cite this article: We found that C. Treatment with the extract resulted in remarkable improvement in thyroid profile. Author information Copyright and License information Disclaimer.

Antihyperglycemic and insulin secretory activity of Costus pictus leaf extract in streptozotocin induced diabetic rats and in in vitro pancreatic islet culture. The IC 50 value of positive control ascorbic acid was found to be 6. Despite this limitation, this model is still used worldwide till date because PTU-induced hypothyroid rat model mimics most of the main features of human hypothyroidism.


After washing, the enzyme—streptavidin—peroxidase was added and finally bound enzyme was detected using the chromogenic substrate TMB. Table 5 Effect of Costus pictus extract on parameters of liver and kidney function in the experimental groups. However, the exact molecular mechanism through which C. Atmospheric pressure chemical ionization; AST: Negative regulation of glucose uptake by Costus pictus in L6 myotube cell line.

Costus pictus ‘Red Stem’

Painted Spiral Ginger can be recognized by its yellow flowers with red spots and stripes. Subscribe to BioSpectrum Asia.

At the end of the study in hypothyroid group, plasma free T3 and free T4 levels were decreased Samples and standards were added to antibody-coated microtiter wells.

Hypothyroidism is one of the most common endocrine diseases. Toxicity studies of the herb Costus pictus D.

In comparison with control, PTU-induced hypothyroid rats exhibited a significant decrease in body weight. The antioxidant capacity of C.